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What is Ankylosing Spondylitis?
What is Ankylosing Spondylitis?
Ankylosing spondylitis (AS) is a chronic condition in which the spine and other areas of the body become inflamed1. Over time, it can cause vertebrae to fuse together.
AS tends to present in patients between 20 and 30 years of age2.
1 in 200 of the UK population is diagnosed with axial AS. It usually takes 8.5 years to get a diagnosis3.
Men are affected more than women4.
What may cause Ankylosing Spondylitis?
The cause is unknown however, in many cases, there is a link to the gene, HLA-B27. Research has shown that 9/10 people (90%) with AS carry the gene variant5.
What are common symptoms?
What are common symptoms?
Chronic back pain and stiffness
Limited range of movement
Arthritis
Enthesitis - inflammation where the bone is joined to a tendon
Fatigue
Associated with other conditions, Uveitis, Psoriasis, and IBD.
Can anything trigger the pain in your interaction?
Can anything trigger the pain in your interaction?
Lack of exercise and movement can increase stiffness. Such as laying for long periods of time on the bed.
To find out more information about Ankylosing spondylitis, visit these websites by clicking the logo
To find out more information about Ankylosing spondylitis, visit these websites by clicking the logo
A patient's Experience
A patient's Experience
If you would like to share your story with Ankylosing Spondylitis. Please contact us.
References
References
[1] - NHS England. Ankylosing Spondylitis [Internet]. England: NHS England; 2022. Available from: https://www.nhs.uk/conditions/ankylosing-spondylitis/
[2] - Sieper J, Poddubnyy D. Axial Spondyloarthritis. Lancet [Internet]. 2017; 390(10089): 73-84. Available from: https://doi.org/10.1016/S0140-6736(16)31591-4
[3] - National Axial Spondyloarthritis Society. Facts and Figures [Internet]. London: NASS; N.D. Available from: https://nass.co.uk/about-as/as-facts-and-figures/
[4] - Dean LE, Jones gt, MacDonald AG. The global prevalence of ankylosing spondylitis. Rheumatology [Internet]. 2014; 53(4): 650-657. Available from: https://doi.org/10.1093/rheumatology/ket387
[5] - Zhu W, He X, Cheng K, Zhang L, Chen D, Wang X, Qiu G, Cao X, Weng X. Ankylosing Spondylitis: etiology, pathogenesis and treatments [Internet]. 2019; 7(22). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804882/
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